NCT01870856

Lid Wiper Epitheliopathy Trial

Evaluation of Lid Wiper Epitheliopathy With and Without Daily Disposable Contact Lenses

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 187 (actual)
• Sponsor: Alcon Research · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the effect of contact lens lubricity on lid wiper epitheliopathy (LWE) in symptomatic contact lens wearers. LWE is defined as an alteration of that portion of the marginal conjunctival epithelium of the upper eyelid that wipes the ocular surface during blinking.

Detailed description

This study will be conducted in two stages. In Stage 1, participants will wear either spectacles or contact lenses for two weeks to determine the impact of interruption of contact lens wear on LWE. In Stage 2, a second cohort of participants will wear one of two contact lens brands for two weeks, and LWE and ocular discomfort will be compared.

Conditions

• Lid Wiper Epitheliopathy

Interventions

Type	Name	Description
DEVICE	Spectacles	Per participant's habitual prescription
DEVICE	Delefilcon A contact lenses	Silicone hydrogel single vision contact lenses
DEVICE	Etafilcon A contact lenses	Hydrogel single vision contact lenses

Timeline

• Start date: 2013-07-01
• Primary completion: 2013-10-01
• Completion: 2013-10-01
• First posted: 2013-06-06
• Last updated: 2014-10-29
• Results posted: 2014-10-29