Trials / Completed
CompletedNCT01870544
Does Weight Loss Surgery and Probiotic Supplementation Lead to a "Lean" Gut Microbiota?
- Status
- Completed
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 18 (actual)
- Sponsor
- Tufts Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the weight-loss study is to characterize the effect of LGG supplementation on the relative abundance of phyla in the gut microbiota of patients undergoing gastric bypass and sleeve gastrectomy surgery, and to elucidate a relationship between the gut microbiota pattern and the degree of weight-loss post-surgery. The investigators hypothesize that LGG administration will result in a "leaner" pattern of gut microbiota that will lead to higher weight loss at 3 months post-surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Lactobacillus Rhamnosus GG | LGG will be administered orally for 44 days |
| DIETARY_SUPPLEMENT | Placebo | placebo will be administered daily for 44 days |
Timeline
- Start date
- 2013-09-01
- Primary completion
- 2016-01-01
- Completion
- 2016-01-01
- First posted
- 2013-06-06
- Last updated
- 2016-02-10
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01870544. Inclusion in this directory is not an endorsement.