NCT01868932

Treating Wheezing in Children With Hypertonic Saline (TWICS)

• Status: Withdrawn
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Dr. Michael Flavin · Academic / Other
• Sex: All
• Age: 2 Days – 6 Years
• Healthy volunteers: Not accepted

Summary

Hypothesis: substitution of nebulized 3% NaCl (HS) for the standard normal saline (NS) used in bronchodilator therapy for acute viral wheezing in all children under age 6 years will provide superior symptom relief leading to decreased admission rates from the Emergency Department. The study will test the efficacy of frequent doses of inhaled bronchodilator co-administered with either 3% hypertonic saline (HS, study group) or 0.9% normal saline (NS, control group) in a prospective, double blind, randomized controlled, multi-centre clinical trial of children under age 6 years presenting to the ED with acute viral-associated wheezing.

Detailed description

the brief summary captures the essence of the study

Conditions

• Wheeze

Interventions

Type	Name	Description
OTHER	hypertonic saline	inhaled nebulized 3%NaCl
OTHER	saline	inhaled nebulized 0.9% NaCl

Timeline

• Start date: 2013-10-01
• Primary completion: 2013-11-01
• Completion: 2013-11-01
• First posted: 2013-06-05
• Last updated: 2015-11-13