NCT01868165

Assessing the Impact of Calcium Channel Blockers on COGnitive Function in the Very Elderly (AI-COG)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 337 (actual)
• Sponsor: Imperial College London · Academic / Other
• Sex: All
• Age: 80 Years
• Healthy volunteers: Not accepted

Summary

Older adults are at increased risk of high blood pressure and cognitive decline. High blood pressure itself also increases risk of cognitive decline. A particular type of blood pressure lowering drug (a calcium channel blocker(CCB)) may lower risk of dementia in younger adults but there is no clear evidence of it's impact in those \>=80. It is important that we know whether CCB use impacts on cognitive function in this age group. This study will examine the impact of antihypertensives on change in cognitive function with a particular focus on CCBs.

Detailed description

This study is an observational cohort study examining cognitive change in those participants taking antihypertensives and aged 80 and over and examining cognitive change in participants taking different types of antihypertensive medication.

Conditions

• Cognitive Ability, General
• High Blood Pressure

Timeline

• Start date: 2013-06-01
• Primary completion: 2015-02-01
• Completion: 2016-02-01
• First posted: 2013-06-04
• Last updated: 2019-09-23
• Results posted: 2019-09-23

Locations

7 sites across 1 country: United Kingdom