NCT01867775

Mirtazapine for Sleep Disorders in Alzheimer's Disease

Mirtazapine for the Treatment of Sleep Disorders in Alzheimer's Disease: a Randomized, Double-blind, Placebo-controlled Study

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Brasilia University Hospital · Academic / Other
• Sex: All
• Age: 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether mirtazapine is effective in the treatment of sleep disorders in Alzheimers disease.

Detailed description

Mirtazapine has been used for depressed elderly with sleep disorders with good tolerability and efficacy. The study hypothesis is that mirtazapine could also be used in demented with sleep disorders. Sleep disorders (SD) affects 35 to 50 percent of patients with Alzheimer Disease (AD). These disorders often make caring for patients at home very difficult and It's also associated with higher risk of institutionalization and increases health care costs. Treatment of SD in people with dementia may benefit both patients and their caregivers. However, little is known about the efficacy of pharmacological treatments for treating sleep disturbances in AD.

Conditions

• Alzheimer's Disease
• Sleep Disorders

Interventions

Type	Name	Description
DRUG	Mirtazapine	Mirtazapine 15 mg, at night, once a day for 14 days

Timeline

• Start date: 2012-05-01
• Primary completion: 2013-12-01
• Completion: 2014-05-01
• First posted: 2013-06-04
• Last updated: 2013-06-04

Locations

1 site across 1 country: Brazil