NCT01867255

Study to Examine the Effect of Gastric Bypass Surgery on Venlafaxine ER Blood Levels

Pharmacokinetic Study Comparing Area Under the Curve for a Single Dose of Venlafaxine ER Pre- and Post-gastric Bypass

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to determine whether a significant and predictable change in bioavailability of extended-release venlafaxine occurs following Roux-en-Y gastric bypass.

Conditions

• Bariatric Surgery
• Gastric Bypass
• Roux-en-Y Gastric Bypass

Interventions

Type	Name	Description
DRUG	venlafaxine ER (extended-release) 75 mg	A single dose of venlafaxine ER 75 mg is to be administered once at each of two study visits, pre- and post-gastric bypass surgery.

Timeline

• Start date: 2013-10-01
• Primary completion: 2015-03-01
• Completion: 2015-03-01
• First posted: 2013-06-03
• Last updated: 2015-12-23

Locations

1 site across 1 country: United States