NCT01865240

Renal Denervation for Resistant Hypertension

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 5 (actual)
• Sponsor: Baker Heart and Diabetes Institute · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

This is a study investigating the effectiveness of renal denervation in lowering blood pressure in people whose blood pressure is not adequately controlled despite treatment with 3 or more blood pressure lowering drugs. The study is designed to compare the effects of renal denervation to a usual care group receiving additional blood pressure lowering drugs.

Detailed description

Previous studies have shown that the renal denervation procedure is safe and effective in reducing blood pressure in patients with resistant hypertension. A total of 100 participants with uncontrolled blood pressure, treated with three or more blood pressure lowering medications will be recruited into the study. Patients will be assigned to one (1) of two (2) groups with the aim of attaining blood pressure control. Participants in group 1 will be assigned to renal denervation, participants in group 2 will receive additional antihypertensive medication according to current guidelines and best practice in an attempt to reach blood pressure targets.

Conditions

• Hypertension

Interventions

Type	Name	Description
DEVICE	Renal Denervation	Renal Denervation Catheter

Timeline

• Start date: 2012-02-01
• Primary completion: 2013-10-01
• Completion: 2013-10-01
• First posted: 2013-05-30
• Last updated: 2018-11-05

Locations

1 site across 1 country: Australia