NCT01864980

Intra-operative Monitoring of Blood Loss

Monitoring of Intraoperative Blood Loss: Benefit of Continuous Noninvasive Haemoglobin Monitoring?

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: University Medical Center Groningen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Certain types of surgery are associated with occult blood loss, which is hard to detect intraoperatively by intermittent conventional, invasive Hb concentration measurements using the clinical standard of Hb monitoring by satellite laboratory analysis (Hbsatlab). The investigators want to see whether continuous non-invasive transcutaneous Hb measurement using a finger sensor (SpHb), (a) reduces the total time (area under the curve, AUC) a patient's Hb is below a predetermined transfusion threshold (HbAUC) for administration of red blood cell concentrate (RBC), and (b) prevents a decrease in total oxygen delivery (DO2) possibly associated with transfusion below a critical haemoglobin concentration. Furthermore, the investigators want to study if SpHb monitoring changes the timing of RBC administration and reduces the need for intra- and post-operative RBC transfusion.

Conditions

• Undetected Intraoperative Blood Loss

Interventions

Type	Name	Description
PROCEDURE	blood transfusion, intermittent Hbsatlab measurement	In the Hbsatlab group, RBC administration and its timing will be based on intermittent Hbsatlab measurement (routine care)
PROCEDURE	blood transfusion, based on continuous SpHb readings	RBC administration and its timing will be based on continuous SpHb readings while Hbsatlab values, measured every 30 min. by an objective observer, will not be visible to the attending anaesthetist.

Timeline

• Start date: 2013-06-01
• Primary completion: 2014-05-01
• Completion: 2014-05-01
• First posted: 2013-05-30
• Last updated: 2015-05-27

Locations

1 site across 1 country: Netherlands