NCT01863706

Misoprostol Versus Oxytocin for Prevention of Post Partum Hemorrhage

Safety and Efficacy of Misoprostol Versus Oxytocin for Prevention of Post Partum Hemorrhage

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: Hormozgan University of Medical Sciences · Academic / Other
• Sex: Female
• Age: 10 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Post partum Hemorrhage (PPH) is one of three main causes of death in pregnant women. Oxytocin is widely used for prevention of PPH. Some studies suggested misoprostol as an alternative treatment when Oxytocin isn't available. The aim of this study is to compare the safety and efficacy of Oxytocin and misoprostol for prevention of PPH.

Detailed description

In a double blind randomized controlled trial 400 pregnant women who has vaginal delivery at Shariati hospital are assigned into two groups either to receive 20 unite oxytocin in 1000cc ringer and 2 placebo tablet or 400mcg oral misoprostol and 2cc normal saline in 1000cc ringer.

Conditions

• Post Partum Hemorrhage

Interventions

Type	Name	Description
DRUG	Misoprostol	400µg oral misoprostol
DRUG	Oxytocin	20 IU Oxytocin

Timeline

• Start date: 2013-05-01
• Primary completion: 2013-12-01
• Completion: 2013-12-01
• First posted: 2013-05-29
• Last updated: 2015-03-26

Locations

1 site across 1 country: Iran