NCT01863173

Effect of Metoprolol on Thalassemia Cardiomyopathy

The Effect of Metoprolol Succinate on the Cardiac Function of Patients With Thalassemia Cardiomyopathy a Double Blind Randomized Study

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: Shiraz University of Medical Sciences · Academic / Other
• Sex: All
• Age: 13 Years – 25 Years
• Healthy volunteers: Not accepted

Summary

effect of B blocker was first evaluated in patient with cardiomyopathy not induced by ischemia and idiopathic which as the most common causes of cardiomyopathy. Effect of BB on Thalassemia cardiomyopathy was evaluated in this study

Detailed description

In this clinical trial, 45 patients with thalassemia cardiomyopathy were randomized to receive either metoprolol (n = 26) or placebo (n = 19). Echocardiography and 6 minute walk test was performed at baseline and repeated after 6 months and the values were compared.

Conditions

• B Thalassemia

Interventions

Type	Name	Description
DRUG	metoprolol	using B blocker in patient group
DRUG	placebo	placebo to control group

Timeline

• Start date: 2012-01-01
• Primary completion: 2012-05-01
• Completion: 2012-12-01
• First posted: 2013-05-27
• Last updated: 2013-05-27

Locations

1 site across 1 country: Iran