Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT01862458

Empyema Treated With tPA & DNAse

Prospective Randomized Trial: Fibrinolysis With tPA (Tissue Plasminogen Activator) Versus tPA and DNAse in Children With Empyema

Status
Withdrawn
Phase
Phase 3
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Children's Mercy Hospital Kansas City · Academic / Other
Sex
All
Age
17 Years
Healthy volunteers
Not accepted

Summary

The objective of this study is to scientifically evaluate a new substrate for fibrinolysis compared to our standard tPA. The hypothesis, driven by a recent prospective trial, is that tPA may benefit from the addition of DNAse. The primary outcome variable between the two techniques will be length of hospitalization after initiation of treatment.

Conditions

Interventions

TypeNameDescription
BIOLOGICALtPA alone
BIOLOGICALtPA plus dornase

Timeline

Start date
2016-01-01
Primary completion
2016-01-01
Completion
2016-01-01
First posted
2013-05-24
Last updated
2016-01-28

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01862458. Inclusion in this directory is not an endorsement.