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Approved For MarketingNCT01861834

Safer Parenteral Nutrition in Pediatric Short Bowel Syndrome to Decrease Liver Damage

A Safer Approach to Total Parenteral Nutrition in Pediatric Short Bowel Syndrome Intended to Decrease the Frequency and Severity of Liver Damage

Status
Approved For Marketing
Phase
Study type
Expanded Access
Enrollment
Sponsor
Georgetown University · Academic / Other
Sex
All
Age
2 Months – 18 Years
Healthy volunteers

Summary

To provide children dependent on total parenteral nutrition with Omegaven®, a fish oil-based intravenous lipid emulsion that may be less hepatotoxic than conventional, vegetable oil-based intravenous lipid emulsions, and that may therefore reduce the need for liver transplantation.

Conditions

Interventions

TypeNameDescription
DRUGOmegaven 10%Patients with a sustained TPN requirement due to short bowel syndrome and TPN-associated liver disease that threatens progression to liver failure and death, for which the only available means of prevention at present is timely liver and/or intestinal transplant. Omegaven 10%, 1 gram/kg, IV, every 12 hours until transplantation, or stopping TPN

Timeline

First posted
2013-05-24
Last updated
2019-05-07

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01861834. Inclusion in this directory is not an endorsement.

Safer Parenteral Nutrition in Pediatric Short Bowel Syndrome to Decrease Liver Damage (NCT01861834) · Clinical Trials Directory