NCT01861353

Cranberry-lingonberry Juice Started During Acute Infection in Prevention of Urinary Tract Infections in Children

Randomized Controlled Trial of the Effect of Cranberry-lingonberry Juice on the Occurrence of Urinary Tract Infections, the Gut Microbiota, and the Uropathogenic Escherichia Coli

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 113 (actual)
• Sponsor: University of Oulu · Academic / Other
• Sex: All
• Age: 1 Year – 16 Years
• Healthy volunteers: Not accepted

Summary

Cranberry and cranberry-lingonberry juice prevented urinary tract infections in children and in adults in our earlier clinical trials. The preventive effect was, however, observed late in the follow-up and the next recurrence was not prevented in children. The investigators hypothesize that cranberry-lingonberry juice should be started already during the antimicrobial treatment of acute urinary tract infection in order to maximize the preventive efficacy of the juice. In addition, the investigators aim to find the explanation for the efficacy of cranberry-lingonberry juice by analyzing the concomitant changes in the chemical composition of urine and feces as well as the changes of gut microbiota.

Conditions

• Urinary Tract Infection
• Pyelonephritis
• Cystitis

Interventions

Type	Name	Description
OTHER	Cranberry-lingonberry juice
OTHER	Placebo juice	Juice iwth similar sugar concentration as cranberry-lingonberry juice but without berry extracts

Timeline

• Start date: 2013-05-01
• Primary completion: 2019-02-28
• Completion: 2019-02-28
• First posted: 2013-05-23
• Last updated: 2022-05-09

Locations

1 site across 1 country: Finland