NCT01859585

Efficacy Parecoxib and Ketorolac as Preemptive Analgesia in Spine Fusion

Comparing the Efficacy of Parecoxib and Ketorolac as Preemptive Analgesia in Patients Undergoing Posterior Lumbar Spinal Fusion

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 96 (actual)
• Sponsor: Prince of Songkla University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the efficacy of Parecoxib and Ketorolac as a preemptive analgesia in patients undergoing lumbar spinal fusion.

Detailed description

A prospective, double-blinded randomized control trial. Randomly allocated patient undergoing posterior lumbar spinal fusion into 3 groups (n=32) to receive Parecoxib, Ketorolac and Placebo around 30 minutes prior to incised skin. Efficacy was assessed by visual analog scale score (0-10), total opioid consumption, complication and bleeding also recorded.

Conditions

• Postoperative Pain

Interventions

Type	Name	Description
DRUG	Parecoxib	Parecoxib 40 mg intravenous
DRUG	Ketorolac	Ketorolac 30 mg intravenous

Timeline

• Start date: 2011-03-01
• Primary completion: 2013-01-01
• Completion: 2013-03-01
• First posted: 2013-05-22
• Last updated: 2013-05-22

Locations

1 site across 1 country: Thailand