NCT01856530

Effect of Oxytocin Nasal Sprays on Social Behavior in Social Anxiety Disorder

Effect of Oxytocin on Pro-Social Behavior in Social Anxiety Disorder

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Stefan G. Hofmann · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to learn more about how the hormone, oxytocin, impacts social behavior in terms of cooperation with others, attention processing, and reward processing, among patients with social anxiety disorder. Based on available research, the investigators predict that in patients with social anxiety disorder, oxytocin will improve social cooperation during an online ball-tossing game called Cyberball, reduce attention toward socially threatening cues during a dot-probe task, and lead to greater willingness to work for monetary rewards for others rather than themselves during an effort expenditure task.

Conditions

• Social Anxiety Disorder

Interventions

Type	Name	Description
DRUG	Oxytocin	Liquid metered-dose nasal spray, 24 IU, administered once
DRUG	Placebo	Matched placebo nasal spray

Timeline

• Start date: 2012-07-01
• Primary completion: 2013-08-01
• Completion: 2013-08-01
• First posted: 2013-05-17
• Last updated: 2018-02-13
• Results posted: 2014-08-15

Locations

1 site across 1 country: United States