Trials / Completed
CompletedNCT01856296
A Study to Select Rational Therapeutics Based on the Analysis of Matched Tumor and Normal Biopsies in Subjects With Advanced Malignancies
WINTHER: A Study to Select Rational Therapeutics Based on the Analysis of Matched Tumor and Normal Biopsies in Subjects With Advanced Malignancies
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 303 (actual)
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
An open non-randomized study using biology driven selection of therapies. WINTHER study will explore matched tumoral and normal tissue biopsies and will use a novel method for predicting efficacy of drugs. The aim is to provide a rational personalized therapeutic choice to all (100 %) patients enrolled in the study, harboring oncogenic events (mutations/ translocations/ amplifications, etc.) or not. The total number of patients treated in the study will be two hundred across all participating cancer centers (European countries -France; Spain-, Israel, USA and Canada). All centers will realize the same study independently.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Biopsy |
Timeline
- Start date
- 2013-04-23
- Primary completion
- 2015-12-07
- Completion
- 2019-02-22
- First posted
- 2013-05-17
- Last updated
- 2019-06-18
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT01856296. Inclusion in this directory is not an endorsement.