Trials / Terminated
TerminatedNCT01856036
Anti-Tumor Immunity Induced by Cryoablation of Invasive Breast Cancers
CHUM-CRYOABLATION: Anti-Tumor Immunity Induced by Cryoablation of Invasive Breast Cancers
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 2 (actual)
- Sponsor
- Saint John's Cancer Institute · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This protocol will study the impact of cryoablation on immune response in patients diagnosed with invasive breast cancers smaller than 1.5 cm. It will profile the immune response to cryoablation of invasive breast cancers. The intra-tumoral and systemic immune response to cryoablation will be determined and compared to pre-ablated breast cancer specimens and historical control specimens.
Detailed description
Patients with small breast cancers will undergo cryoablation of their breast cancer. Approximately six weeks after cryoablation, definitive breast surgery will be performed. Blood will be drawn for research before cryoablation and surgery and at regular follow-up visits. Blood and tissue samples will be used to determine immune responses.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Cryoablation | Cryoablation of breast cancer will be performed using a freeze-thaw technique and an IceCure probe. Cryoablation cycles will be determined by IceCure software programmed by the treating surgeon. |
Timeline
- Start date
- 2013-04-01
- Primary completion
- 2014-10-01
- Completion
- 2014-10-01
- First posted
- 2013-05-17
- Last updated
- 2017-02-07
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01856036. Inclusion in this directory is not an endorsement.