NCT01855243

Comparison on Efficacy and Safety of Three Inpatient Insulin Therapy in Type2 DM

Premix 70/30 Insulin Plus Supplemental Lunch Insulin in Comparison to Basal Plus Prandial Supplemental Scale and Sliding Scale Insulin in Hospitalized Patients With Type 2 Diabetes

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 63 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

Purpose: To compare efficacy and safety of traditional sliding scale insulin (SSI) versus modified 70/30 insulin versus modified basal plus supplemental scale /bolus insulin regimens for glycemic control in hospitalized diabetic patients with diabetes. Methods: In a prospective trial, patients with diabetes will be randomized to receive either traditional hospital SSI , or twice daily 70/30 insulin plus supplemental lunchtime insulin for BG ≥ 150 mg/dL or once every night glargine plus three times prandial glulisine for BG ≥ 150 mg/dL . 70/30 insulin and glargine will be started respectively at 0.4 and 0.2 U/kg/day for BG ≤ 200 mg/dL or 0.5 and 0.3 U/kg/day for BG above 200 mg/dL.

Conditions

• Diabetes Mellitus (DM)

Interventions

Type	Name	Description
DRUG	regular insulin
DRUG	70/30 insulin
DRUG	Glargine
DRUG	glulisine

Timeline

• Start date: 2010-03-01
• Primary completion: 2014-02-01
• Completion: 2014-06-01
• First posted: 2013-05-16
• Last updated: 2019-01-15
• Results posted: 2019-01-15

Locations

1 site across 1 country: Egypt