NCT01854723

Comparison Study of Insulin Glargine and NPH Insulin

Basal Insulin Therapy in Patients With Insulin Resistance: A 6 Month Comparison of Insulin Glargine and NPH Insulin

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Providence Health & Services · Academic / Other
• Sex: All
• Age: 85 Years
• Healthy volunteers: Accepted

Summary

This study will compare the safety, effectiveness, and cost of two different types of long-acting insulin.

Detailed description

In this study the investigators will be comparing two long-acting insulins, insulin glargine and NPH insulin. The trial will be evaluating differences in effectiveness, safety and cost between the two agents when used in patients on more than 80 units or 1unit/kg long-acting insulin. The investigators hypothesis is that patients switched from lantus to NPH will have improved blood glucose control.

Conditions

• Diabetes

Interventions

Type	Name	Description
DRUG	Switching to NPH insulin	Patients in this arm will be transitioned from insulin glargine to NPH insulin with subsequent titration according to algorithm within protocol. If needed, meal-time insulin will be added during study period.
DRUG	Continuation of insulin glargine	Patients in this group will serve as a control group, and information will be collected regarding the safety, effectiveness, and cost of treatment for use in this study.

Timeline

• Start date: 2013-04-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2013-05-15
• Last updated: 2020-03-10

Locations

1 site across 1 country: United States