NCT01853696

Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty

Prospective, Randomized Comparison of Corticosteroid Dosing Regimens Following Endothelial Keratoplasty

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 167 (actual)
• Sponsor: Cornea Research Foundation of America · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Graft rejection has traditionally been one of the leading causes of cornea transplant failure. To help prevent rejection, corticosteroid eye drops are used for an extended period after transplant surgery. The purpose of this study is to compare the efficacy and side effects of different corticosteroid dosing regimens after endothelial keratoplasty (cornea transplant) surgery.

Conditions

• Fuchs' Dystrophy
• Corneal Edema

Interventions

Type	Name	Description
DRUG	loteprednol etabonate
DRUG	prednisolone acetate 1%

Timeline

• Start date: 2013-03-01
• Primary completion: 2015-01-01
• Completion: 2015-01-01
• First posted: 2013-05-15
• Last updated: 2015-05-15
• Results posted: 2015-04-30

Locations

1 site across 1 country: United States