NCT01850485

Microcirculatory Perfusion in Patients With Coma After Out-of-hospital Cardiac Arrest

Microcirculatory Perfusion as Measured by Sublingual SDF Imaging and NIRS in Patients With Coma After Out-of-hospital Cardiac Arrest Treated With Mild Therapeutic Hypothermia (TH) or Not Treated With Mild-TH

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 22 (actual)
• Sponsor: Frisius Medisch Centrum · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The hypothesis is: In patients after an out of hospital cardiac arrest, treated with therapeutic hypothermia (33°C) will be found significantly more microcirculatory abnormalities, compared to the same group of patients treated with 36°C.

Detailed description

The purpose of this study is to investigate the (sublingual) microcirculation in patients after an out of hospital cardiac arrest (OHCA). The microcirculation is measured in this study by Sublingual Side Stream Darkfield (SDF) Imaging and Near InfraRed Spectroscopy (NIRS) at admission and after 12 and 24 hours.

Conditions

• Cardiac Arrest

Interventions

Type	Name	Description
DEVICE	microcirculation by SDF and NIRS, in 33 and 36 degrees	at baseline, after 12 and 24 hours in both arms

Timeline

• Start date: 2012-02-01
• Primary completion: 2013-01-01
• Completion: 2013-05-01
• First posted: 2013-05-09
• Last updated: 2015-06-25
• Results posted: 2015-06-25

Locations

1 site across 1 country: Netherlands