Clinical Trials Directory

Trials / Completed

CompletedNCT01849562

Safety, Tolerability, and Efficacy of 12-weeks of Sovaprevir, ACH-3102, and Ribavirin in Treatment-naive GT-1 HCV Participants

A Phase 2a Trial to Evaluate the Safety, Tolerability, and Efficacy of 12 Weeks of Sovaprevir, ACH-0143102 and Ribavirin in Treatment-Naive Subjects With Chronic Hepatitis C Genotype-1 Viral Infection

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
30 (actual)
Sponsor
Alexion Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study was to evaluate the safety, tolerability, and efficacy of 12 weeks of treatment with sovaprevir, ACH-0143102, and ribavirin (RBV) in genotype-1 (GT-1), treatment-naive, hepatitis C virus (HCV) participants.

Conditions

Interventions

TypeNameDescription
DRUGSovaprevirNonstructural protein 3/4A protease inhibitor.
DRUGACH-3102Nonstructural protein 5A inhibitor.
DRUGRibavirin
DRUGPlacebo

Timeline

Start date
2013-04-01
Primary completion
2013-11-01
Completion
2014-04-01
First posted
2013-05-08
Last updated
2023-08-29
Results posted
2015-02-04

Source: ClinicalTrials.gov record NCT01849562. Inclusion in this directory is not an endorsement.