NCT01846923

B Memory Cell Response to Vaccination With the 13-valent Pneumococcal Conjugate Vaccine in Asplenic Individuals

Study of the B Memory Cell Response to Vaccination With the 13-valent Pneumococcal Conjugate Vaccine in Asplenic Individuals With Beta-thalassemia Major

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 37 (actual)
• Sponsor: Aghia Sophia Children's Hospital of Athens · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether one dose of the 13-valent pneumococcal conjugate vaccine (PCV13) induces immunological memory in asplenic adults and whether previously administered immunizations with the 23-valent polysaccharide pneumococcal vaccine influence the cellular immune response to PCV13 in this group.

Conditions

• Asplenia
• β-thalassemia Major

Interventions

Type	Name	Description
BIOLOGICAL	PCV13

Timeline

• Start date: 2010-10-01
• Primary completion: 2012-02-01
• First posted: 2013-05-06
• Last updated: 2013-05-06

Locations

1 site across 1 country: Greece