Clinical Trials Directory

Trials / Completed

CompletedNCT01846143

Evaluation of a Multi-phosphopeptide Vaccine Plus PolyICLC in Participants With High Risk and Advanced Malignancies

Evaluation of the Safety and Immunogenicity of a Multi-phosphopeptide Vaccine Plus PolyICLC in Participants With High Risk and Advanced Malignancies (Mel59)

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
15 (actual)
Sponsor
Craig L Slingluff, Jr · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to learn what effects (good and bad) experimental phosphopeptide vaccines plus a tetanus peptide and other substances called polyICLC and Montanide ISA-51 have on people with melanoma. The investigators will also look at whether the experimental reagents cause any changes in the immune system.

Conditions

Interventions

TypeNameDescription
BIOLOGICALpBCAR3-phosphopeptide
BIOLOGICALpIRS2-phosphopeptide
BIOLOGICAL2-MpP (pBCAR3-phosphopeptide + pIRS2-phosphopeptide)

Timeline

Start date
2013-05-01
Primary completion
2015-06-01
Completion
2015-11-01
First posted
2013-05-03
Last updated
2016-08-12

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01846143. Inclusion in this directory is not an endorsement.

Evaluation of a Multi-phosphopeptide Vaccine Plus PolyICLC in Participants With High Risk and Advanced Malignancies (NCT01846143) · Clinical Trials Directory