NCT01844362

Uterus Transplantation From Live Donor

Prospective Case Series of Human Uterus Transplantation From Live Donor

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: Sahlgrenska University Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 39 Years
• Healthy volunteers: Accepted

Summary

Uterus transplantation, as a possible future treatment for uterine factor infertility, has been developed in animal species during the last decade. The study protocol includes transplantation of the uterus from a live donor (mother, relative, friend) into women with absolute uterine factor infertility (lack of uterus from birth or due to life saving hysterectomy).The recipient will be treated by standard immunosuppression and transfer of embryos (acquired by IVF before surgery) will be attempted when at least 12 months have passed from transplantation. Approval for a case series including up to 10 patients has been acquired.

Detailed description

The study is ongoing, with inclusion of 9 patients.

Conditions

• Primary Uterine Infertility

Interventions

Type	Name	Description
PROCEDURE	uterine transplantation	Transplantation of the uterus from live donor and IVF treatment.

Timeline

• Start date: 2012-09-01
• Primary completion: 2018-04-01
• Completion: 2021-12-01
• First posted: 2013-05-01
• Last updated: 2024-06-24

Locations

1 site across 1 country: Sweden