NCT01840982

The Effects of Mixed Grain on Blood Glucose and Insulin in Healthy Male

A Randomized, Crossover Clinical Trial, The Effects of Mixed Grain on Blood Glucose and Insulin in Healthy Male

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Chonbuk National University Hospital · Academic / Other
• Sex: Male
• Age: 19 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study was an open, 4-treatment, 5-sequence, 5-day cross-over randomized design clinical trial to evaluate the efficacy of mixed grain on blood glucose, insulin and Glycemic index(GI) in healthy males.

Detailed description

After a 12-hour fast, oral glucose or meal tolerance test was performed with blood samples drawn at time 0, 15, 30, 45, 90, 120, 150, and 180 min. 1. Serum levels of glucose, insulin, and C-peptide were analyzed by biochemical autoanalyzer. The area under the curve (AUC) changes in blood glucose were computed by the trapezoidal method. 2. Glycemic index(GI): the area under the glucose response curve after consumption of a test food divided by the area under the curve after consumption of a control food containing the same amount of carbohydrate and calculated using 50 g glucose as the reference.

Conditions

• Healthy People
• Diabetes Mellitus, Type 2

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Mixed grain 1	All test foods contained 50 g available carbohydrate from the test food products. A glass of 200 ml water was served together with the clinical trial food, and the participants were instructed to ingest the breakfast with 15 min.
DIETARY_SUPPLEMENT	Mixed grain 2	All test foods contained 50 g available carbohydrate from the test food products. A glass of 200 ml water was served together with the clinical trial food, and the participants were instructed to ingest the breakfast with 15 min.
DIETARY_SUPPLEMENT	White rice	All test foods contained 50 g available carbohydrate from the test food products. A glass of 200 ml water was served together with the clinical trial food, and the participants were instructed to ingest the breakfast with 15 min.
OTHER	Glucose solution	All test foods contained 50 g available carbohydrate from the test food products.

Timeline

• Start date: 2010-10-01
• Primary completion: 2010-11-01
• Completion: 2015-03-25
• First posted: 2013-04-26
• Last updated: 2019-08-07

Locations

1 site across 1 country: South Korea