NCT01837446

Morphine Mouthwash for Management of Oral Mucositis in Patients With Head and Neck Cancer

Evaluating the Effectiveness of Topical Morphine Compared With a Routine Mouthwash in Managing Cancer Treatment-induced Mucositis in Patients With Head and Neck Cancer in Isfahan

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Isfahan University of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Oral mucositis is a debilitating side effects of cancer treatment for which there is not much successful treatments at yet. The investigators are going to evaluate the effectiveness of topical morphine compared with a routine mouthwash in managing cancer treatment-induced mucositis. The investigators hypothesize that topical morphine is more effective and more satisfied by patients than the magic mouthwash in reducing severity of cancer treatment-induced oral mucositis.

Conditions

• Stomatitis

Interventions

Type	Name	Description
DRUG	2% morphine solution
DRUG	Magnesium aluminum hydroxide
DRUG	2% viscous lidocaine
DRUG	Diphenhydramine

Timeline

• Start date: 2011-07-01
• Primary completion: 2012-07-01
• Completion: 2012-10-01
• First posted: 2013-04-23
• Last updated: 2013-04-23

Locations

1 site across 1 country: Iran