NCT01835639

Vitamin D Supplementation in Glomerular Disease

Pilot Study: Efficacy and Safety of Vitamin D Supplementation in Glomerular Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Children's Hospital of Philadelphia · Academic / Other
• Sex: All
• Age: 5 Years – 30 Years
• Healthy volunteers: Not accepted

Summary

This multi-site, pilot study will assess vitamin D supplementation in children and young adults with Glomerular Disease. .

Detailed description

Vitamin D deficiency has been linked to a variety of adverse health outcomes. Nephrotic patients have very low vitamin D levels, and the underlying mechanisms are not known. Furthermore, approaches to safely and effectively supplement vitamin D in these patients have not been established. The purpose of this research study is to learn if vitamin D supplementation is safe and effective in patients with primary glomerular disease and to also help establish the treatment guidelines. About 35 patients with primary glomerular disease, ages 5-30 years old, will take part in this study. Participants will be asked to take vitamin D supplements each day for 12 weeks and will have 3 study visits.

Conditions

• Glomerular Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Cholecalciferol, 2000 or 4000 IUs by mouth daily for 12 weeks	Supplements will be provided as oral capsules.

Timeline

• Start date: 2013-04-01
• Primary completion: 2017-09-01
• Completion: 2017-09-01
• First posted: 2013-04-19
• Last updated: 2019-08-12

Locations

5 sites across 1 country: United States