Clinical Trials Directory

Trials / Terminated

TerminatedNCT01834937

ExAblate Treatment of Metastatic Bone Tumors for the Palliation of Pain

A Post Approval Registry: ExAblate Treatment of Metastatic Bone Tumors for the Palliation of Pain

Status
Terminated
Phase
Study type
Observational
Enrollment
17 (actual)
Sponsor
InSightec · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this enhanced surveillance study ("ESS") is to collect information regarding chronic adverse events that are possibly related to the ExAblate® System ("ExAblate") that are received by InSightec ("InSightec") following PMA approval. This study will examine adverse events reported in patients undergoing the device procedure for the first two years of commercial experience. Other relevant data may be collected as well.

Detailed description

This proposed Registry will be performed in full compliance with all HIPAA rules and their implementations at potential participating sites. All patients planned to undergo the ExAblate procedure in a commercial setting after PMA approval will be offered a consent so they can be included in the ESS. Non-consenting patients will not be included in the ESS. However, information regarding the total number of subjects treated at each participating site with the device will also be collected. InSightec will set up a (password protected) EDC database for the sites to enter the information of participating subjects treated with the ExAblate device from all U.S. sites using the ExAblate procedure for the bone metastases indication. This will occur for a total duration of 2 years following device approval. It should be noted that any adverse event that meets the Medical Device Report ("MDR") definition will be reported as an MDR as well. There will be no control group. Reporting to FDA will occur at six-month intervals for the first two-years after PMA approval.

Conditions

Interventions

TypeNameDescription
DEVICEExAblate MRgFUS (Magnetic Resonance guided Focused Ultrasound Surgery)Focused Ultrasound Surgery - FUS delivered by ExAblate for the palliation of pain due to bone metastases.

Timeline

Start date
2013-06-01
Primary completion
2017-04-01
Completion
2017-04-01
First posted
2013-04-18
Last updated
2018-11-09

Locations

6 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01834937. Inclusion in this directory is not an endorsement.