NCT01831284

Correlates and Consequences of Increased Immune Activation in Injection Drug Users

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 201 (actual)
• Sponsor: Rockefeller University · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The goal of this study is to learn how injection drug use may affect the immune system.

Detailed description

The goal of this study is to learn how injection drug use may affect the immune system. One way to measure this is by looking at the blood and the gut, or gastrointestinal tract at the same time. It is thought that activating the immune system by injection drug use may increase destruction of immune cells in the gut. To test this theory, the investigators are enrolling HIV-negative injection drug users, HIV-negative people who do not use drugs and HIV-negative former injection drug users.

Conditions

• Intravenous Drug Usage

Interventions

Type	Name	Description
PROCEDURE	Sigmoidoscopy with biopsy	Sigmoidoscopy with biopsy

Timeline

• Start date: 2012-12-01
• Primary completion: 2014-09-01
• Completion: 2014-09-01
• First posted: 2013-04-15
• Last updated: 2014-11-06

Locations

1 site across 1 country: United States