NCT01830192

REM (Risk Of Endometrial Malignancy)

REM (Risk Of Endometrial Malignancy): A Proposal for a New Scoring System to Evaluate Risk of Endometrial Malignancy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 741 (actual)
• Sponsor: Campus Bio-Medico University · Academic / Other
• Sex: Female
• Age: 45 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to obtain a predictive model to asses the Risk of Endometrial Malignancy (REM) in women with ultrasound endometrial abnormalities.

Detailed description

Objective: It is often difficult to distinguish a benign endometrial disease from a malignancy and tools to help physician are needed, in order to triage patients into high and low risk of endometrial cancer (EC). The purpose of this study was to obtain a predictive model to asses the Risk of Endometrial Malignancy (REM) in women with ultrasound endometrial abnormalities.Women, between 45 and 80 years, diagnosed with ultrasound endometrial abnormalities and scheduled to have surgery were enrolled on a prospective study at Department of Gynaecologic Oncology of Campus Bio-Medico of Rome. Preoperative clinical, ultrasound and laboratory features were taken into account. Logistic regression algorithm was utilized to categorize patients into low and high risk groups for EC.

Conditions

• Endometrial Disease

Interventions

Type	Name	Description
OTHER	Training set	We evaluate the clinical, ultrasound and laboratory features to predict endometrial cancer disease preoperative
OTHER	VERIFICATION SET	We evaluate the clinical, ultrasound and laboratory features to predict endometrial cancer disease preoperative

Timeline

• Start date: 2010-01-01
• Primary completion: 2012-11-01
• Completion: 2012-12-01
• First posted: 2013-04-12
• Last updated: 2013-04-12

Locations

1 site across 1 country: Italy