NCT01829685

Efficacy Optimizing Extension Study of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapy

A 3-year, Open-lable, Multi-center Extension Trial of Entecavir Therapy for Patients Previously Treated in Dragon Study

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 360 (estimated)
• Sponsor: Nanfang Hospital, Southern Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the long-term efficacy and safety of entecavir 1.0 mg/d + adefovir 10 mg/d with entecavir 0.5 mg/d + adefovir 10 mg/d for chronic hepatitis B patients with inadequate response to NUC therapy

Conditions

• Chronic Hepatitis B
• Inadequate Response
• Nucleos(t)Ide Analogues Treatment

Interventions

Type	Name	Description
DRUG	Entecavir, Adefovir

Timeline

• Start date: 2013-03-01
• Primary completion: 2016-06-01
• First posted: 2013-04-11
• Last updated: 2014-06-19

Locations

16 sites across 1 country: China