NCT01829542

Dose-dependent Effects of Blueberry Polyphenols on Endothelial Function in Healthy Individuals

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: University of Reading · Academic / Other
• Sex: Male
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess the impact of acute blueberry polyphenol intake on endothelial function of healthy volunteers. Specifically, the investigators plan to perform a randomised, double blind, cross-over human intervention trial using a blueberry drink to investigate the dose-dependent effects of blueberry polyphenols on blood vessel function using Flow mediated dilation (FMD) to measure endothelial function. The study will not only measure the acute effects of flavonoid ingestion on vascular reactivity but will also assess plasma polyphenol metabolite levels.

Conditions

• Endothelial Function

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Freeze-dried blueberry powder dissolved in water	Wild blueberry freeze-dried powder dissolved in water
DIETARY_SUPPLEMENT	Control	Macro- and micro-nutrient matched control in water

Timeline

• Start date: 2012-05-01
• Primary completion: 2012-08-01
• Completion: 2012-10-01
• First posted: 2013-04-11
• Last updated: 2013-04-11

Locations

1 site across 1 country: United Kingdom