NCT01829009

Resistance Exercise Effect on Physical Performance and Functional Status in Sarcopenic Older Women

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: National Institute of Medical Sciences and Nutrition, Salvador Zubiran · Academic / Other
• Sex: Female
• Age: 70 Years
• Healthy volunteers: Not accepted

Summary

Aging is characterized by a progressive loss of multiple physical and cognitive abilities. From these changes, the most important one is the loss of muscle mass, which has been called "sarcopenia". Resistance exercise is a therapeutic approach for sarcopenia, nevertheless there is no universal consensus. Therefore, this research is interested in determining the effect of a resistance exercise program on physical performance and/or functional status in sarcopenic older women. The main study hypothesis is that a program of resistance exercise will improve physical performance and functional status in sarcopenic older women compared against general recommendations. This is a single-blind, controlled clinical trial, including women\> 70 years, living in the community with sarcopenia. Those who agree to participate, will be randomly assigned to one of the following groups: 1. Resistance Exercise Group 2. General Recommendations Group (control) The study will last 24 weeks, with 4 measurements performed at baseline, week 6, 12 and 24. Multilevel models (random effects) will be constructed for the comparison between the two groups. Tests will be conducted with a P=0.05 and confidence intervals at 95%. This protocol has been approved by the local ethics committee.

Detailed description

Study withdrawn.

Conditions

• Sarcopenia

Interventions

Type	Name	Description
OTHER	Resistance Exercise Group	An individualized resistance exercise program wil be applied twice a week by an expert physiotherapist. Every 2 weeks, intensity will be reassessed by the same physiotherapist. Weekly, participants will be asked about incidents such as the occurrence of falls or hospitalizations during this study period. Physical performance and functional status will be assessed by the blind investigator at weeks 6,12 and 24

Timeline

• Primary completion: 2013-04-01
• First posted: 2013-04-11
• Last updated: 2015-04-22

Locations

1 site across 1 country: Mexico