Trials / Completed
CompletedNCT01827579
Infusion of Depleted T Cells Following Unrelated Donor Stem Cell Transplant (ICAT)
Adoptive Immunotherapy With CD25/71 Allodepleted Donor T Cells to Improve Immunity After Unrelated Donor Stem Cell Transplant
- Status
- Completed
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 37 (actual)
- Sponsor
- University College, London · Academic / Other
- Sex
- All
- Age
- 16 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate whether the administration of allodepleted donor T cells to patients with haematological malignancies after stem cell transplant can improve the recovery of the patients immune system.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | CD25/71 allodepleted donor T-cells | CD25/71 allodepleted donor T-cells will be administered at a dose of 10\^5 /kg at day 30 post-SCT, 3 x 10\^5 /kg at day 60 and 10\^6 /kg at day 90 post transplant |
Timeline
- Start date
- 2014-07-01
- Primary completion
- 2020-01-01
- Completion
- 2020-01-01
- First posted
- 2013-04-09
- Last updated
- 2022-07-21
Locations
2 sites across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT01827579. Inclusion in this directory is not an endorsement.