NCT01827332

Effect of Oxytocin on Craving and Therapy Response

Effect of Oxytocin on Craving and Therapy Response in Marijuana-dependent Individuals

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to examine the impact of a medication called oxytocin on marijuana use and therapy response in people who frequently use marijuana.

Detailed description

Oxytocin has been shown to promote trust, social bonding, and calmness; however, its potential additive effects with a therapy intervention have not been explored in marijuana-dependent individuals. In the proposed study, the impact of intranasal oxytocin on therapy effectiveness and marijuana use outcomes following a brief therapy intervention will be investigated. It is hypothesized that oxytocin administration (vs. placebo) will improve treatment satisfaction and decrease marijuana use.

Conditions

• Marijuana Dependence

Interventions

Type	Name	Description
DRUG	Oxytocin	Subjects will be administered 40 IUs of oxytocin nasal spray or matching placebo prior to two individual sessions of MET.
DRUG	Saline	Subjects will be administered 40 IUs of oxytocin nasal spray or matching placebo prior to two individual sessions of MET.

Timeline

• Start date: 2013-03-01
• Primary completion: 2015-06-01
• Completion: 2016-07-01
• First posted: 2013-04-09
• Last updated: 2017-01-02
• Results posted: 2016-11-11

Locations

1 site across 1 country: United States