NCT01827098

A Clinical Study to Compare Two Revascularization Protocols to Treat Non-vital Teeth With Incomplete Root Formation

A Randomized Controlled Clinical Trial of Regenerative Protocols to Treat Immature Necrotic Teeth

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 6 Years – 25 Years
• Healthy volunteers: Not accepted

Summary

Both methods tested in this study disinfect the non-vital root canals and induce blood clot formation inside the root canal. One method places calcium hydroxide inside the root canal after disinfection and the blood clot is induced four weeks later. The other method performs disinfection and induction of blood clot in one appointment. The investigators hypothesize that both methods will obtain the same success rate in eliminating infection, increase in root length and canal walls thickness.

Detailed description

Collagen is placed on top of the blood clot, followed by white MTA. Glass ionomer is used to seal the access to the canal, which will be replaced by a permanent restoration 3 months later.

Conditions

• Dental Pulp Necrosis
• Disorder of Tooth Development

Interventions

Type	Name	Description
PROCEDURE	Endodontic Regeneration	Blood clot formation is induced in the root canal after disinfection. Collagen material is placed over the clot. The canal access is sealed with white MTA and glass ionomer restoration. Permanent restoration is placed 3 months later on top of the MTA.

Timeline

• Start date: 2012-10-01
• Primary completion: 2023-06-07
• Completion: 2023-06-07
• First posted: 2013-04-09
• Last updated: 2023-07-11

Locations

1 site across 1 country: United States