NCT01823328

Ketamine Versus Etomidate for Rapid Sequence Intubation

Ketamine Versus Etomidate for Sedation of Emergency Department Patients During Rapid Sequence Intubation

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 143 (actual)
• Sponsor: Hennepin Healthcare Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).

Detailed description

This study is a randomized controlled trial of etomidate versus ketamine during rapid sequence intubation (RSI). RSI refers to the process by which patients who require emergency airway management undergo sedation and paralysis prior to insertion of an endotracheal tube(airway tube). Patients who require intubation will be randomized to have intubation performed with either ketamine or etomidate. All other care will be at the discretion of the treating physicians. The purpose of this study is to compare the efficacy and safety of ketamine and etomidate during rapid sequence intubation.

Conditions

• Airway Control
• Anesthesia
• Intubation
• Complication

Interventions

Type	Name	Description
DRUG	Ketamine	Subjects will receive ketamine for sedation prior to rapid sequence intubation.
DRUG	Etomidate	Subjects will receive etomidate for sedation prior to rapid sequence intubation.

Timeline

• Start date: 2013-09-01
• Primary completion: 2015-10-01
• Completion: 2015-10-01
• First posted: 2013-04-04
• Last updated: 2019-05-24
• Results posted: 2019-05-24

Locations

1 site across 1 country: United States