Clinical Trials Directory

Trials / Terminated

TerminatedNCT01820078

Paricalcitol on Albuminuria, Inflammation and Fibrosis on Proteinuric Chronic Renal Diseases (PALIFE Study)

Effect of Paricalcitol on Albuminuria, Inflammation and Fibrosis on Proteinuric Chronic Renal Diseases (PALIFE Study): a Randomized Study

Status
Terminated
Phase
Phase 4
Study type
Interventional
Enrollment
127 (actual)
Sponsor
Fundación Renal Iñigo Alvarez De Toledo · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to estimate the differences between albuminuria values determined as Urine Albumin-to-Creatinine Ratio (UACR)(log transformed) from baseline to last observation caused by paricalcitol between the group of control and group of treatment.

Detailed description

Clinical Trial to estimate UACR determined albuminuria differences between treatment and non-treatment groups from basal intake to last study-related observation. Patients should suffer proteinuric Chronical Kidney Disease and recovered levels of seric 25(OH)D. Also, this clinical trial tries to determinate the effect of paricalcitol over several metabolic and inflammatory parameters on patients.

Conditions

Interventions

TypeNameDescription
DRUGExperimental armOral paricalcitol, 1 ug/day, plus daily treatment. 6 months (all study)
OTHERComparator ArmDaily treatment is not define by protocol, because daily treatment in CKD is highly variable and includes salt and/or blood pressure regulation, angiotensine system stoppers, controlled diet, etc.

Timeline

Start date
2012-05-01
Primary completion
2013-09-01
Completion
2013-12-01
First posted
2013-03-28
Last updated
2013-11-28

Locations

25 sites across 1 country: Spain

Source: ClinicalTrials.gov record NCT01820078. Inclusion in this directory is not an endorsement.