Trials / Unknown
UnknownNCT01819545
The Study of microRNA 107 (miRNA 107) and Beta-amyloid Precursor Protein-cleaving Enzyme 1 (BACE1) Messenger Ribonucleic Acid (mRNA) Gene Expression in Cerebrospinal Fluid and Peripheral Blood of Alzheimer's Disease
Shanghai Mental Health Center
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 300 (estimated)
- Sponsor
- Shanghai Mental Health Center · Academic / Other
- Sex
- All
- Age
- 60 Years – 90 Years
- Healthy volunteers
- Accepted
Summary
The miRNA 107 gene is increasingly appreciated to serve key functions in humans. The miRNA regulate gene expression involved in cell division, metabolism, stress response, and angiogenesis in vertebrate species. But the relationship and diagnosis capability of miRNA 107 and BACE1 mRNA gene expression in plasma and cerebrospinal fluid (CSF) of amnestic mild cognitive impairment (aMCI) and normal control is still a mystery.
Detailed description
The Real-Time PCR was the main method in the research.
Conditions
Timeline
- Start date
- 2012-01-01
- Primary completion
- 2014-07-01
- Completion
- 2015-12-01
- First posted
- 2013-03-27
- Last updated
- 2014-02-19
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT01819545. Inclusion in this directory is not an endorsement.