NCT01819532

Milking the Umbilical Cord Versus Immediate Clamping in Pre-term Infants < 33 Weeks

Milking the Umbilical Cord Versus Immediate Clamping in Pre-term Infants <33 Weeks: A Randomized Controlled Trial

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: Female
• Age: 15 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Anemia in preterm neonates is a significant problem encountered frequently in the neonatal intensive care unit. Most preterm neonates born at less than 33 weeks gestation will require at least one blood transfusion during their hospital course and many will require repeated transfusions. Blood transfusions, albeit necessary, carry increased risk of viral infections and transfusion reactions as well as increase the cost of healthcare. The umbilical cord and placenta harbor up to 40% of blood available during fetal life. The current standard of care is immediate umbilical cord clamping. The investigators are performing a randomized controlled trial comparing immediate cord clamping to milking the umbilical cord prior to clamping in neonate born preterm less than 33 weeks gestation. The investigators hypothesize that milking the umbilical cord will demonstrate the same benefits as delayed cord clamping, without delaying neonatal resuscitation.

Conditions

• Prematurity

Interventions

Type	Name	Description
PROCEDURE	Milking group	The umbilical cord will be "milked" toward the neonate four times prior to clamping the umbilical cord.
PROCEDURE	Immediate cord clamping	The umbilical cord will be clamped and cut immediately after delivery of the neonate.

Timeline

• Start date: 2011-09-01
• Primary completion: 2013-10-01
• Completion: 2013-10-01
• First posted: 2013-03-27
• Last updated: 2017-12-11

Locations

1 site across 1 country: United States