NCT01819350

In Vivo Study of Sucrose and Liquid Oral Pediatric Medicines of Long-term Effect on Dental Biofilm pH

Avaliação in Vivo do Potencial cariogênico e Erosivo de Bebidas e Medicamentos pediátricos líquidos Intra-orais

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Federal University of Paraíba · Academic / Other
• Sex: All
• Age: 18 Years – 22 Years
• Healthy volunteers: Accepted

Summary

The aims of this study were to determine the sucrose and liquid oral pediatric medicines of long-term effect on dental biofilm pH to evaluate the cariogenic potential in vivo.

Detailed description

Te study was carried out with 12 subjects that were refrained from brushing their teeth for 28 h and did not eat or drink for at least 3 h prior to each appointment. Dental biofilm pH was measured in the cervical and proximal regions of anterior teeth with beetrode-type microelectrode coupled to a potentiometer. The biofilm was submitted nine paediatric medicines a long term and sucrose (negative control). pH measurements were taken at baseline to determine resting plaque pH and at time interval 5, 10, 15, 20, 25 and 30 minutes.

Conditions

• Dental Biofilm pH

Interventions

Type	Name	Description
OTHER	G1, G2 and G3	Nutritional, respiratory and endocrine group applicated 12 subjects
OTHER	G4 and G5	Application of trhree pediadic medidines of antibiotic group on dental biofilm 12 subjects

Timeline

• Start date: 2011-08-01
• Primary completion: 2012-02-01
• Completion: 2012-08-01
• First posted: 2013-03-27
• Last updated: 2013-03-27

Locations

1 site across 1 country: Brazil