Clinical Trials Directory

Trials / Completed

CompletedNCT01818596

Open-label Safety Study of E/C/F/TAF (Genvoya®) in HIV-1 Positive Patients With Mild to Moderate Renal Impairment

A Phase 3 Open-label Safety Study of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Single-Tablet Regimen in HIV-1 Positive Patients With Mild to Moderate Renal Impairment

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
252 (actual)
Sponsor
Gilead Sciences · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary objective of this study is to evaluate the effect of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) fixed-dose combination (FDC) tablet on renal parameters at Week 24 in treatment-naive and treatment-experienced HIV-positive, adults with mild to moderate renal impairment.

Conditions

Interventions

TypeNameDescription
DRUGE/C/F/TAFE/C/F/TAF (150/150/200/10 mg) FDC tablet administered orally once daily with food

Timeline

Start date
2013-03-27
Primary completion
2014-07-31
Completion
2018-07-18
First posted
2013-03-26
Last updated
2020-03-02
Results posted
2016-02-18

Locations

70 sites across 9 countries: United States, Australia, Dominican Republic, France, Mexico, Netherlands, Spain, Thailand, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT01818596. Inclusion in this directory is not an endorsement.

Open-label Safety Study of E/C/F/TAF (Genvoya®) in HIV-1 Positive Patients With Mild to Moderate Renal Impairment (NCT01818596) · Clinical Trials Directory