NCT01815996

Identify Clinical Conditions That Increase Circulating DNA Levels

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 130 (actual)
• Sponsor: University of Florida · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The investigators are developing a test that is expected to measure the amount of radiation a patient has been exposed to after a nuclear bomb. The investigator will do this by measuring the DNA in the patients blood from cells killed by the radiation. Many diseases and medical conditions can put DNA in the blood. The investigator needs to know how much DNA in order to better interpret our radiation detection test. Therefore, the investigator is collecting blood from several patients with different diseases or medical conditions and also healthy volunteers to measure their DNA content. Patients that will be included in this study are pregnant women, patients who have suffered a pulmonary embolism within the past 48 hours, patients who have suffered from myocardial infarction in the past 48 hours, patients with autoimmune diseases and health patients.

Detailed description

The investigator will collect 8 mL (one and one half teaspoons) of blood one time only. The investigator may also collect the patient's past medical history, test results and disease treatment.

Conditions

• Pregnancy
• Pulmonary Embolism
• Myocardial Infarction
• Autoimmune Disease

Interventions

Type	Name	Description
OTHER	One time blood draw to look at patient's DNA	One time blood draw to look at patient's DNA

Timeline

• Start date: 2012-10-01
• Primary completion: 2016-07-28
• Completion: 2016-07-28
• First posted: 2013-03-21
• Last updated: 2018-11-21

Locations

1 site across 1 country: United States