NCT01815216

Effect of Gastric Bypass Surgery on Brain Responses

The Effects of Bariatric Surgery on Impulsivity and Attentional Bias to Food Cues

• Status: Suspended
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (estimated)
• Sponsor: Uppsala University · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

After obesity surgery gastric bypass (GBP) patients usually lose more than 50% of its former preponderance in relative short time (\~ 2 years). But knowledge of the underlying biological mechanisms of decline in body weight is still inadequate. This project intends to examine patients' background activity in the brain (i.e. "the resting state activity") and brain volume using MRI both before and one year after surgery.

Detailed description

We will also investigate whether hormonal changes in response to food intake after obesity surgery is associated with patients' impulsive control when exposed to pictures of food in the MRI.

Conditions

• Obesity
• Hormone Responses
• Cognitive Health

Interventions

Type	Name	Description
PROCEDURE	Bariatric surgery	Gastric bypass surgery
BEHAVIORAL	Brain activity in resting state	Measure of activity in brain networks during resting state
BEHAVIORAL	Memory performance	Assess concentration in 2D-location task (i.e. "memory game")

Timeline

• Start date: 2013-03-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2013-03-20
• Last updated: 2015-06-02

Locations

1 site across 1 country: Sweden