Trials / Unknown
UnknownNCT01810796
Pathophysiology and Prevention of Perioperative Myocardial Injury: A Prospective Randomized Controlled Trial
- Status
- Unknown
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 300 (estimated)
- Sponsor
- Hadassah Medical Organization · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Working hypothesis and aims: 1) To explore the pathophysiology of postoperative troponin elevations and 2) whether ranolazine, a new anti-ischemic drug that has no effect on blood pressure or heart rate, prevents postoperative myocardial injury.
Detailed description
High-risk patients undergoing non cardiac surgery will be randomized to receive either Ranolazine or placebo perioperatively and troponin will be measured on the first 3 days after surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ranolazine | Ranolazine versus placebo |
Timeline
- Start date
- 2013-12-01
- Primary completion
- 2016-12-01
- Completion
- 2017-12-01
- First posted
- 2013-03-14
- Last updated
- 2013-03-14
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT01810796. Inclusion in this directory is not an endorsement.