Trials / Completed
CompletedNCT01809093
Thrombospondin-1 and Pigmented Epithelium Derived Factor Levels in Patients With Diabetes Mellitus.
Modulation of Thrombospondin-1 and Pigment Epithelium Derived Factor Levels in Vitreous Fluid and Plasma of Patients With Diabetes
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 90 (actual)
- Sponsor
- MidAtlantic Retina · Academic / Other
- Sex
- All
- Age
- 18 Minutes
- Healthy volunteers
- Not accepted
Summary
You are being asked to be in a research study to determine blood levels and vitreous levels of compounds called thrombospondin 1 (TSP1) and pigment epithelium derived factor (PEDF). These compounds exists naturally in your body.
Detailed description
The hypothesis tested here is that diabetic patients that express the higher molecular weight pigment epithelium-derived factor (PEDF) isoform have lower thrombospondin-1 (TSP1) level and, as a result, are at a greater risk for the development of more severe diabetic retinopathy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Blood draw | 3-4 tablespoons of blood will be drawn, one time. |
Timeline
- Start date
- 2010-03-01
- Primary completion
- 2014-03-01
- Completion
- 2014-03-01
- First posted
- 2013-03-12
- Last updated
- 2017-02-23
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01809093. Inclusion in this directory is not an endorsement.