Clinical Trials Directory

Trials / Completed

CompletedNCT01808144

Lesinurad and Febuxostat Combination Extension Study in Gout

A Long-Term Extension Study of Lesinurad in Combination With Febuxostat for Subjects With Gout Completing an Efficacy and Safety Study of Lesinurad and Febuxostat

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
196 (actual)
Sponsor
Ardea Biosciences, Inc. · Industry
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

This study will assess the serum uric acid lowering effects and safety of lesinurad in combination with febuxostat over a long-term timeframe.

Detailed description

This is a Phase 3 extension study to assess the long-term efficacy and safety of lesinurad in combination with febuxostat in subjects who completed the double-blind treatment period in Study RDEA594-304.

Conditions

Interventions

TypeNameDescription
DRUGlesinuradTablets, 400 mg once daily (QD)
DRUGlesinuradTablets, 200 mg QD
DRUGfebuxostatTabletsm 80 mg QD

Timeline

Start date
2013-03-01
Primary completion
2016-08-09
Completion
2016-10-06
First posted
2013-03-11
Last updated
2018-01-30
Results posted
2018-01-30

Locations

72 sites across 6 countries: United States, Australia, Canada, New Zealand, Poland, Switzerland

Source: ClinicalTrials.gov record NCT01808144. Inclusion in this directory is not an endorsement.