NCT01804660

Longitudinal Therapeutically Non-interventional Study of MSRV-Env Burden in Normal Population

A One Year Longitudinal Therapeutically Non-Interventional Study of MSRV-Env Burden in Normal Population as Assessed by PCR and ELISA in Blood

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 25 (actual)
• Sponsor: GeNeuro Innovation SAS · Industry
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study intends to explore the levels of MSRV expression by analyzing the levels of MSRV transcripts in blood, as well as the levels of the MSRV-Env protein in serum in the normal population. This study is important for establishing a baseline to analyze results obtained in MS patients (another dedicated study is performed in parallel in MS patients). The study will be conducted over one year in a cohort of healthy subjects. The MSRV RNA level, MSRV-Env protein levels, reverse transcriptase activity, inflammatory markers assessed by cytokines levels will be analysed to define control levels in the normal population and their variation during one year. The data obtained in this study in healthy controls will be compared to those obtained in a parallel similar study, GN-E-002, conducted in different types of MS patients.

Conditions

• Multiple Sclerosis

Interventions

Type	Name	Description
OTHER	No study treatments administered

Timeline

• Start date: 2012-10-01
• Primary completion: 2013-11-01
• Completion: 2013-12-01
• First posted: 2013-03-05
• Last updated: 2020-10-20

Locations

1 site across 1 country: France