NCT01801722

Using NT-proBNP to Detect Chronic Heart Failure in Patients With Chronic Obstructive Pulmonary Disease

Using NT-proBNP to Detect Chronic Heart Failure in Patients With Chronic Obstructive Pulmonary Disease.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 75 (actual)
• Sponsor: Lund University · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of the present study was to evaluate if the analysis of NT-proBNP might be used as an initial step for the diagnosis of chronic heart failure in patients with COPD in primary health care, and to select patients for a further examination by echocardiography.

Detailed description

Patients with a confirmed diagnosis of COPD were examined regarding chronic heart failure. 1. An interview regarding symptoms: breathlessness, orthopnoea, night cough, nocturia, walking distance. 2. Physical examination: weight and height, heart and lung auscultation, blood pressure measurement after 5 minutes' rest in the sitting position and the presence of peripheral oedema. 3. Electrocardiography. 4. Natriuretic peptide- NT-proBNP (Immulite 2500, Siemens Healthcare Diagnostics AB Sweden). 5. Patients with the NT-proBNP level of \> 1200 pg/ml were referred for echocardiography to assess left ventricular function.

Conditions

• Chronic Obstructive Pulmonary Disease
• Chronic Heart Failure

Timeline

• Start date: 2008-04-01
• Primary completion: 2008-06-01
• Completion: 2008-06-01
• First posted: 2013-03-01
• Last updated: 2018-03-07

Locations

1 site across 1 country: Sweden